Biostimulators in Raleigh, NC


Collagen Restoration for Facial Aging, Weight Loss & Skin Laxity
Aging and Weight loss can be life-changing — but when it happens rapidly, especially with GLP-1 medications like semaglutide or tirzepatide, the face is often the first place patients notice unintended changes.
Laxity in the face is one of the most difficult things to treat in the face. It's something that cannot even be solved with Plastic surgery alone. At Blossüm Aesthetics, we specialize in biostimulatory treatments that restore collagen, structure, and skin quality — not by overfilling, but by helping your body rebuild what was lost.
What Are Biostimulators?
Biostimulators are injectable treatments designed to stimulate your body’s own collagen production over time.
Unlike traditional dermal fillers that add immediate volume, biostimulators work gradually to:
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Improve skin thickness and elasticity
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Restore facial structure
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Strengthen the dermal foundation
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Support long-term facial aging prevention
This makes them ideal for patients experiencing:
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Facial thinning
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Skin laxity
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Volume loss from aging or weight loss
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“Ozempic Face” or GLP-1 related changes
Sculptra® vs. Hyper-Dilute Radiesse®
Understanding the Difference (and Why We Often Use Both)
Both Sculptra and Hyper-Dilute Radiesse are biostimulatory injectables — but they work differently and serve different purposes.
Sculptra®Made of poly-L-lactic acid (PLLA)Stimulates collagen through an immune-mediated responseProduces a thicker, deeper collagen build
Best for: Cheeks, Temples, Jawline, Global facial volume loss. Sculptra is ideal for structural support and deep volume restoration.

Hyper-Dilute Radiesse®Made of calcium hydroxylapatite (CaHA)When diluted, acts as a skin regenerative treatment. Reactivates fibroblasts (collagen + elastin producers)Best for: Skin laxity, Texture and crepiness, Neck, lower face, chest. Hyper-Dilute Radiesse focuses on skin quality rather than volume.
Our Approach at Blossüm Aesthetics
At Blossüm, we don’t choose treatments based on trends or brand names — we choose them based on what your face actually needs.
Most patients benefit from combination therapy:
Sculptra → deep support + structure
Hyper-Dilute Radiesse → skin quality + firmness
Together, they rebuild the face from the inside out — creating results that look natural now and continue to improve over time.
How GLP-1 Weight Loss Affects the Face
GLP-1 medications are incredibly effective — but they don’t discriminate where fat is lost.
As weight drops, patients often notice:
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Hollowed cheeks and temples
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Looser skin along the jawline
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Increased fine lines and wrinkles
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A tired or aged facial appearance
This happens because facial fat pads provide youthful structure, and when they shrink quickly, skin doesn’t always rebound on its own.
That’s where biostimulators play a critical role.

Why Biostimulators Are Ideal for GLP-1 Patients
For patients on GLP-1 medications, we focus on supporting the skin as the body changes, not reacting after damage has already occurred.
Biostimulators help by:
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Rebuilding collagen lost during rapid weight loss
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Improving skin firmness and elasticity
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Preventing premature sagging
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Restoring balance without making the face look “filled”
They are especially powerful when combined with RF microneedling and microneedling, which further stimulate collagen at different skin depths.
What to Expect from Biostimulator Treatment
Your appointment typically includes:
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Comprehensive facial assessment
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Review of weight loss history (including GLP-1 use)
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Customized treatment plan
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Targeted injections
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Long-term maintenance strategy
Results develop gradually over weeks to months as collagen production increases.
How Long do Biostimulators Last?
Longevity depends on:
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Product used
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Areas treated
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Individual collagen response
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Lifestyle and metabolism
Most patients enjoy results that last 1–2+ years, making biostimulators one of the most durable rejuvenation options available.
Why Patients Choose Blossüm for Biostimulators in Raleigh
Patients travel from all over because results aren’t dependent on:
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A specific device
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A filler brand
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A one-size-fits-all protocol
They trust us because of our:
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Assessment-driven approach
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Deep anatomical understanding
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Conservative, long-term philosophy
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Consistent, natural results
Every plan is curated for the future version of your face, not just today.



